Why Diseases Appear to Skip Generations
Diseases caused by genetic factors are controlled by alleles, which are versions of the same gene that code for different characteristics. Every person will receive one allele from each parent. These may be different or the same and each is typically either dominant or recessive. The influence of a dominant allele will overpower that of a recessive allele. One example of how alleles work to influence disease is the genetic basis of conditions that are known to be autosomal recessive. Sickle cell disease is an autosomal recessive condition. The gene that is responsible for sickle cell, HBB, has many possible…